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Updated: Jul 3, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Spontaneous sphenoid sinus meningocele with associated amenorrhea and headache: illustrative case
Deveney Franklin1, Ali S Yamani2, Andre E Boyke3
11School of Medicine, University of North Carolina, Chapel Hill, North Carolina.
Background:
Developmental meningoceles of the sphenoid sinus are uncommon. When encountered, they are often associated with cerebrospinal fluid (CSF) rhinorrhea.
Observations:
The authors present the case of a 27-year-old female with a large meningocele eroding through the sella turcica and sphenoid sinus into the nasopharynx. The patient presented with intractable headaches and amenorrhea without CSF rhinorrhea.
Lessons:
The patient underwent an endoscopic endonasal transsphenoidal reduction of the meningocele with reelevation of the pituitary gland and skull base reconstruction with abdominal fat graft and nasoseptal flap.
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