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[Which augmentation and trigger factors are relevant in urticaria?]

Julia Zarnowski1, Regina Treudler2,3

  • 1Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig A.ö.R., Philipp-Rosenthal-Str. 69, 04103, Leipzig, Deutschland. julia.zarnowski@medizin.uni-leipzig.de.

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Summary

This review details factors triggering or worsening urticaria, focusing on chronic spontaneous urticaria. Key triggers include medications, stress, food, comorbidities, infections, and hormonal changes.

Keywords:
Acute urticariaAggravationChronic spontaneous urticariaDisease modificationExacerbation

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Area of Science:

  • Dermatology
  • Immunology

Context:

  • Urticaria encompasses acute and chronic inducible forms, with a significant focus on chronic spontaneous urticaria (CSU).
  • Understanding exacerbating factors is crucial for managing CSU effectively.

Purpose:

  • To review current literature on factors that trigger or augment urticaria.
  • To specifically discuss aggravating elements in chronic spontaneous urticaria.

Summary:

  • Identifies key factors influencing urticaria, including medication, stress, diet, psychological and metabolic conditions, infections, inflammation, and hormonal fluctuations.
  • Highlights the complex interplay of internal and external triggers in CSU pathogenesis.

Impact:

  • Provides a comprehensive overview for clinicians and researchers on urticaria exacerbation.
  • Aids in developing targeted management strategies for patients with chronic urticaria.