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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Vincazalidine A, a unique bisindole alkaloid from Catharanthus roseus

Yusuke Hirasawa1, Ayaka Kase2, Akie Okamoto2

  • 1Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-Ku, Tokyo, 142-8501, Japan. y-hirasawa@hoshi.ac.jp.

Journal of Natural Medicines
|February 12, 2024
PubMed

Keywords:
Catharanthus roseusApoptosisBisindole alkaloidCell proliferationCytotoxic activityDP4 statistical analysisVincazalidine A

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