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Published on: September 12, 2019
Applicability of the PedsQLTM 4.0 Generic and Fatigue Modules in Romanian Children with Inflammatory Bowel Disease:
Andreea Ioan1, Mara-Ioana Ionescu1,2, Catalin Boboc1
1Department of Pediatrics, Marie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.
Insights
The Romanian PedsQL tool reliably measures health-related quality of life and fatigue in children with inflammatory bowel disease (IBD), showing lower quality of life in affected children.
Area of Science:
- Pediatric Health Outcomes
- Quality of Life Measurement
- Gastroenterology
Background:
- The Pediatric Quality of Life (PedsQL) Inventory assesses Health Related Quality of Life (HRQoL) in children.
- This study evaluated the Romanian PedsQL Generic Core and Multidimensional Fatigue Scales in children with Inflammatory Bowel Disease (IBD).
Discussion:
- The Romanian PedsQL demonstrated feasibility and reliability in assessing HRQoL and fatigue in pediatric IBD patients.
- Results showed significantly lower HRQoL and higher fatigue levels in children with IBD compared to healthy controls.
- The tool exhibited good internal consistency (>0.70) with minimal missing data.
Key Insights:
- The PedsQL effectively differentiates between children with IBD and healthy controls regarding HRQoL and fatigue.
- Validated Romanian versions of PedsQL modules are crucial for assessing pediatric IBD patient well-being.
- Lower HRQoL and increased fatigue are key indicators in pediatric IBD.
Outlook:
- Further multi-centric studies with larger cohorts are needed to fully validate the PedsQL modules for clinical activity severity correlation.
- Expanding the use of validated PedsQL tools can improve patient-centered care in pediatric gastroenterology.
- Future research should focus on longitudinal studies to track HRQoL changes in pediatric IBD over time.
Abstract:
The Pediatric Quality of Life (PedsQL) Inventory is a tool used to measure Health Related Quality of Life (HRQoL) in children aged 2 to 18 years. The aim of the present study was to investigate the feasibility and reliability of the Romanian version of two PedsQL modules, the Generic Core and the Multidimensional Fatigue Scales, in children with inflammatory bowel disease (IBD). Children diagnosed with IBD in our clinic and their parents completed a total of 26 Romanian version PedsQL forms, while a control group of healthy children and their caregiver filled in 86 identical online forms. We compared total and dimensional scores between controls and subjects, along with age, sex, and active versus inactive disease differences. The results indicated that the PedsQL total and summary scores differentiated between subjects and controls, with lower HRQoL and higher levels of fatigue being reported in children with chronic IBD. The Romanian version of the PedsQL was found to be feasible and reliable, with good internal consistency higher than 0.70 and minimum missing responses. However, the limited number of participants meant that clinical activity severity indices correlated poorly with fatigue and generic scores. Further validation of these models requires larger, multi-centric studies.
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