The ClearPoint Array Frame: An MRI Compatible System that Supports Non-craniotomy, Multi-trajectory (NCMT)...

Area of Science:

• Neurosurgery
• Oncology
• Medical Devices

Background:

• Stereotactic neurosurgery is evolving with complex multi-trajectory approaches.
• The ClearPoint SmartFrame Array is a second-generation MRI-compatible stereotactic frame designed for advanced procedures.

Purpose of the Study:

• To prospectively evaluate the safety and clinical utility of the ClearPoint SmartFrame Array for non-craniotomy, multi-trajectory (NCMT) stereotactic procedures.
• To establish the feasibility of NCMT procedures in neuro-oncology.

Main Methods:

• Ten consecutive patients underwent NCMT stereotactic procedures, including biopsy and laser interstitial thermal therapy, targeting distinct neoplastic regions.
• Procedures were performed under a single anesthetic event using the ClearPoint SmartFrame Array.

Main Results:

• The median maximal radial error was 1.0 mm, indicating high accuracy.
• Definitive diagnoses were achieved in all cases, with >90% of targets ablated.
• No procedural complications occurred, with a median hospital stay of 1 day and no 30-day readmissions.

Conclusions:

• The ClearPoint Array frame safely and accurately facilitates NCMT stereotactic procedures.
• This technique allows access to geographically distinct regions of brain cancer.