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Updated: May 6, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

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The role of periprocedural hemodynamic variables during carotid stenting for the mid-term general mortality in

Teodora Yaneva-Sirakova1, Galina Zlatancheva1, Kiril Karamfiloff2

  • 1Acibadem City Clinic Cardiovascular Center, Sofia University, Sofia, Bulgaria.

Folia Medica
|February 14, 2024
PubMed

Insights

Carotid stenting can cause bradycardia and hypotension, especially in elderly patients. These effects may negatively impact brain blood flow in high-risk individuals.

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Interventional Cardiology

Background:

  • Carotid artery stenting is a procedure to open blocked carotid arteries.
  • Elderly patients undergoing carotid stenting are at higher risk for complications.
  • Cerebral hemodynamics in these patients may be compromised due to age and risk factors.

Purpose of the Study:

  • To investigate the physiological effects of carotid stenting.
  • To understand the impact of bradycardia and hypotension on elderly patients.
  • To assess the adaptive capacity of cerebral hemodynamics in high-risk individuals.

Main Methods:

  • Observational study monitoring hemodynamic parameters during carotid stenting.
  • Analysis of heart rate and blood pressure changes.
  • Assessment of cerebral blood flow indicators.

Main Results:

  • Carotid stenting frequently leads to significant bradycardia and hypotension.
  • Elderly high-risk patients exhibit reduced capacity to adapt their cerebral hemodynamics.
  • These hemodynamic changes can have detrimental short- and long-term consequences.

Conclusions:

  • Carotid stenting poses risks of bradycardia and hypotension in elderly patients.
  • Compromised cerebral hemodynamics in this population exacerbates these risks.
  • Careful monitoring and management are crucial for high-risk patients undergoing carotid stenting.
Abstract

Keywords:
neurological outcome systolic blood pressure drops

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