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A general platform for targeting MHC-II antigens via a single loop

Haotian Du1, Jingjia Liu2, Kevin M Jude3

  • 1Department of Chemistry, Stanford University, Stanford, CA, USA.

Biorxiv : the Preprint Server for Biology
|February 14, 2024
PubMed
Summary

A new protein platform, TRACeR-II, enables rapid development of specific MHC-II binders for targeting antigens. This versatile system overcomes challenges in developing high-affinity, antigen-specific MHC-II targeting systems.

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