Related Experiment Video

Updated: Jul 3, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
08:27

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

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Using Alternative Definitions of Controls to Increase Statistical Power in GWAS

Sarah E Benstock, Katherine Weaver, John Hettema

    Research Square
    |February 14, 2024
    PubMed
    Summary

    This study introduces an ordinal model for genome-wide association studies (GWAS), enhancing statistical power by redefining case-control outcomes. This approach boosts power, comparable to a 10% sample size increase, for genetic discovery.

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