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Invasiveness of previous treatment for peripheral arterial disease and risk of adverse cardiac events after coronary stenting

  • 0Department of Cardiology, Thoraxcentrum Twente (A25), Medisch Spectrum Twente, Koningsplein 1, 7512 KZ, Enschede, The Netherlands.
Cardiovascular Intervention and Therapeutics +

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February 14, 2024

|

February 14, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Patients with peripheral arterial disease (PADs) undergoing percutaneous coronary intervention (PCI) face risks. This study found that the invasiveness of prior PADs treatment did not significantly impact adverse event risks after PCI.

Area Of Science

  • Cardiology
  • Vascular Surgery
  • Interventional Cardiology

Background

  • Patients with peripheral arterial disease (PADs) undergoing percutaneous coronary intervention (PCI) have increased risks of adverse events.
  • The influence of the invasiveness of previous PADs treatment on PCI outcomes remains unclear.

Purpose Of The Study

  • To evaluate the impact of invasive versus non-invasive PADs treatment on adverse event risks following PCI with drug-eluting stents.

Main Methods

  • A post-hoc analysis of pooled 3-year patient-level data from PCI all-comer patients in the eastern Netherlands.
  • PADs included atherosclerotic lesions in extremities, carotid, vertebral, mesenteric arteries, or aorta.
  • Invasive treatments included surgery or angioplasty; non-invasive treatments included medication and exercise programs.

Main Results

  • Of 357 PCI patients with PADs, 249 (69.7%) received invasive treatment and 108 (30.3%) received non-invasive treatment.
  • No significant differences were observed in target vessel failure (20.5% vs. 16.0%), major adverse cardiac events (23.3% vs. 20.4%), or all-cause mortality (12.1% vs. 8.3%) between groups.
  • The invasiveness of PADs treatment was not associated with 3-year adverse event risks after PCI.

Conclusions

  • In patients undergoing PCI, the invasiveness of prior PADs treatment does not significantly alter 3-year outcomes.
  • High-risk PCI patients with PADs can be identified by the presence of PADs, regardless of treatment invasiveness.

Keywords:

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