Related Experiment Video
Updated: Jul 3, 2025
04:33
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
682
Cognitive Symptoms of Post-COVID-19 Condition and Daily Functioning
Abhishek Jaywant1, Faith M Gunning1, Lauren E Oberlin1
1Department of Psychiatry, Weill Cornell Medicine, New York, New York.
JAMA Network Open
|February 14, 2024
Summary
Cognitive symptoms are prevalent in post-COVID-19 condition, impacting daily functioning and employment. Addressing these symptoms is crucial for public health responses to long COVID.
Area of Science:
- Neurology
- Public Health
- Infectious Diseases
Background:
- Cognitive symptoms are frequently reported in post-COVID-19 condition but lack comprehensive characterization regarding demographic and functional factors in generalizable populations.
- Understanding these factors is essential for effective management and public health strategies.
Purpose of the Study:
- To determine the prevalence of self-reported cognitive symptoms in individuals with post-COVID-19 condition.
- To compare cognitive symptom prevalence with individuals who had acute SARS-CoV-2 infection but no post-COVID-19 condition.
- To examine the association of cognitive symptoms with depressive symptoms and functional status.
Main Methods:
- A 50-state, nonprobability, population-based internet survey was conducted in two waves between December 2022 and May 2023.
- Participants included 14,767 adults aged 18+ who reported test-confirmed COVID-19 at least two months prior.
- Cognitive symptoms were assessed using the Neuro-QoL cognition battery, and depressive symptoms were measured by the Patient Health Questionnaire-9.
Main Results:
- Of 1683 individuals with post-COVID-19 condition, 56.7% reported daily cognitive symptoms versus 27.1% in those without post-COVID-19 condition.
- Daily cognitive symptoms correlated with increased functional interference (AOR, 1.30), reduced full-time employment (AOR, 0.92), and higher depressive symptom severity (coefficient, 1.27).
- These associations remained significant after accounting for depressive symptoms.
Conclusions:
- Cognitive symptoms are common in post-COVID-19 condition and are linked to significant functional impairment, reduced employment, and increased depressive symptoms.
- Screening for and addressing cognitive symptoms should be an integral part of the public health response to post-COVID-19 condition.
- These findings highlight the need for targeted interventions for cognitive dysfunction in long COVID patients.
Related Concept Videos
01:30Negative and Cognitive Symptoms of Schizophrenia
48
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
48
01:30Cognitive Development During Adulthood
109
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
109
01:30Positive Symptoms of Schizophrenia: Hallucinations and Delusions
114
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
114
01:14Role of Cerebellum and Prefrontal Cortex in Memory
430
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
430
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.8K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.8K
01:28Obsessive-Compulsive Disorder
130
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
130