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High-throughput Flow Cytometry Cell-based Assay to Detect Antibodies to N-Methyl-D-aspartate Receptor or Dopamine-2 Receptor in Human Serum
Published on: November 23, 2013
Ovarian teratoma-associated anti-NMDA receptor encephalitis with severe features
Antanina Voit1, Ashley Graziano2, Andrew Schomer2
1Department of Anesthesiology, University of Virginia Health System, Charlottesville, Virginia, USA agh4qz@uvahealth.org.
Abstract:
Anti-N-methyl-D-aspartame receptor (NMDAR) encephalitis is an uncommon clinical entity for the general intensivist or neurologist. Diagnosis can be made by the presence of cerebrospinal fluid IgG antibody against the GluNR1 and GluNR2 subunits of the NMDAR. We present a case of anti-NMDAR encephalitis in a young woman with an ovarian teratoma treated with surgical resection and multiple immunomodulatory therapies.
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