Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Evidence for Evolution02:55

The Evidence for Evolution

42.7K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
42.7K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

126
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
126
Data Collection by Experiments01:13

Data Collection by Experiments

24.2K
Data collection is a systematic method of obtaining, observing, measuring, and analyzing accurate information. An experimental study is a standard method of data collection that involves the manipulation of the samples by applying some form of treatment prior to data collection. It refers to manipulating one variable to determine its changes on another variable. The sample subjected to treatment is known as “experimental units.”
An example of the experimental method is a public...
24.2K
Criteria for Causality: Bradford Hill Criteria - II01:28

Criteria for Causality: Bradford Hill Criteria - II

313
The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
313
Bootstrapping01:24

Bootstrapping

606
The term "bootstrap" originated in the 19th century as a metaphor for self-improvement or achieving something independently, without external assistance. This concept extends to statistical bootstrapping, a self-contained method for estimating population parameters through resampling, even though it can be computationally intensive. Developed by the American statistician Dr. Bradley Efron in 1979, bootstrapping provides a robust way to perform inference when the original sample size is...
606
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

128
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
128

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Boys surpass girls in maths in the first year of school.

Nature·2025
Same author

The next generation of experimental research with LLMs.

Nature human behaviour·2025
Same author

High-frequency location data show that race affects citations and fines for speeding.

Science (New York, N.Y.)·2025
Same author

Measuring racial educational disparities over time amongst top achievers.

Nature·2025
Same author

Critical thinking and misinformation vulnerability: experimental evidence from Colombia.

PNAS nexus·2024
Same author

Megastudy shows that reminders boost vaccination but adding free rides does not.

Nature·2024
Same journal

Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer.

Nature·2026
Same journal

Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies.

Nature·2026
Same journal

Vaccination elicits HIV broadly neutralizing antibodies in primates.

Nature·2026
Same journal

Child online safety needs more than social-media bans.

Nature·2026
Same journal

Ebola preparedness must start with ecosystems and before humans show symptoms.

Nature·2026
Same journal

AI tools can speed up thinking, but evidence still comes from the lab bench.

Nature·2026
See all related articles

Related Experiment Video

Updated: Jul 3, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.2K

Optimally generate policy-based evidence before scaling.

John A List1,2,3

  • 1The University of Chicago, Chicago, IL, USA. jlist@uchicago.edu.

Nature
|February 15, 2024
PubMed
Summary
This summary is machine-generated.

To improve policy scaling, generate evidence optimally by asking what information is needed and when. This approach, grounded in scaling science, helps reduce the

More Related Videos

Watershed Planning within a Quantitative Scenario Analysis Framework
12:44

Watershed Planning within a Quantitative Scenario Analysis Framework

Published on: July 24, 2016

8.0K
Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

3.7K

Related Experiment Videos

Last Updated: Jul 3, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.2K
Watershed Planning within a Quantitative Scenario Analysis Framework
12:44

Watershed Planning within a Quantitative Scenario Analysis Framework

Published on: July 24, 2016

8.0K
Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

3.7K

Area of Science:

  • Social sciences
  • Behavioral economics
  • Policy implementation

Background:

  • Scaling social interventions often results in a 'voltage drop,' where cost-benefit profiles diminish.
  • Effective policy scaling is crucial for community health, safety, and future opportunities.

Purpose of the Study:

  • To propose an optimal strategy for generating policy-based evidence to mitigate scaling 'voltage drops.'
  • To reframe the social science research model to align with the demands of scaling science.

Main Methods:

  • Advocating for a shift in the traditional research model.
  • Augmenting efficacy trials with integrated tests of scale during the discovery phase.

Main Results:

  • Optimal evidence generation requires defining what information is needed and its sequence.
  • Integrating scale tests early forces a "big picture" recognition of scaling confidence requirements.

Conclusions:

  • Flipping the traditional research model can reduce policy scaling 'voltage drops.'
  • Prioritizing scale-relevant evidence generation from the outset is key for successful policy implementation.