Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

At-Home Versus in-Clinic Vital Capacity Measurement: Insights From the HEALEY ALS Platform Trial.

Muscle & nerve·2026
Same author

From Atomic Layers to Moire Superlattices: Engineering Quantum Interfaces in 2D Heterostructures for Next Generation Terahertz Optoelectronics.

Small methods·2026
Same author

MXene-Reinforced 3D-Printed Biomatrices: Synthesis, Characterization, and Intelligent Theragenerative Applications.

ACS applied materials & interfaces·2026
Same author

Metallic nanoparticles: from biosynthesis to biomedical applications, current scenarios and prospects.

Nanoscale advances·2026
Same author

Targeting Vascular Dementia: Pharmacological Mechanisms and Therapeutic Strategies.

CNS & neurological disorders drug targets·2026
Same author

Early face deprivation leads to long-lasting deficits in cortical face processing.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Jul 3, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

2.3K

Polyacrylonitrile as a versatile matrix for gold nanoparticle-based SERS substrates.

Saloni Sharma1, Rajesh Kumar2, Ram Manohar Yadav1,3

  • 1Department of Physics, VSSD College, CSJM University Kanpur 208002 U.P. India.

Nanoscale Advances
|February 15, 2024
PubMed
Summary

Researchers developed polyacrylonitrile/gold nanoparticle (PAN/AuNPs) composite porous films for ultrasensitive surface-enhanced Raman spectroscopy (SERS) detection. These films efficiently detect methylene blue dye at low concentrations, showing great potential for chemical and biological sensing.

More Related Videos

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

1.9K
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

2.6K

Related Experiment Videos

Last Updated: Jul 3, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

2.3K
Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

1.9K
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

2.6K

Area of Science:

  • Materials Science
  • Spectroscopy
  • Nanotechnology

Background:

  • Surface-enhanced Raman spectroscopy (SERS) requires highly sensitive substrates for molecule detection.
  • Developing efficient and responsive SERS substrates is crucial for advancing analytical techniques.

Purpose of the Study:

  • To prepare and characterize polyacrylonitrile/gold nanoparticle (PAN/AuNPs) composite porous films.
  • To evaluate the efficacy of these films as SERS substrates for detecting methylene blue (MB) dye.

Main Methods:

  • Fabrication of PAN/AuNPs composite porous films using a dip coating technique.
  • Characterization of film morphology and composition using Scanning Electron Microscopy (SEM) and X-ray Diffraction (XRD).
  • UV-vis absorption spectroscopy to confirm the presence of gold nanoparticles (AuNPs).

Main Results:

  • The prepared films exhibited a highly porous structure with uniformly dispersed AuNPs.
  • XRD and UV-vis spectra confirmed the successful incorporation of AuNPs.
  • The PAN/AuNPs SERS substrates detected 50 nM methylene blue dye with a significant Raman peak enhancement.
  • An enhancement factor (EF) of approximately 10^6 was achieved for MB detection.

Conclusions:

  • PAN/AuNPs composite porous films are effective and reliable SERS substrates.
  • These substrates demonstrate excellent sensitivity and potential for detecting trace analytes.
  • The developed films show promise for applications in chemical and biological sensing.