Risk factors of recurrent thyroid nodules after radiofrequency ablation
Yuke Xia1, Yuehe Fu1, Mengjia Qian1
1Department of Thyroid and Breast Surgery, The Affiliated Jiangning Hospital of Nanjing Medical University, 211100, Nanjing, China.
African Health Sciences
|February 15, 2024
Summary
Thyroid nodule recurrence after radiofrequency ablation is linked to solitary nodules, larger nodule diameter, and risky nodule location. Recurrent laryngeal nerve injury was not a predictive factor. These findings aid in preventing recurrence.
Area of Science:
- Endocrinology
- Interventional Radiology
- Oncology
Background:
- Radiofrequency ablation (RFA) is a common treatment for thyroid nodules.
- Understanding recurrence risk factors is crucial for optimizing patient outcomes and treatment strategies.
Purpose of the Study:
- To identify independent risk factors for thyroid nodule recurrence following RFA.
- To evaluate the predictive value of identified factors using ROC analysis.
Main Methods:
- Retrospective analysis of 120 patients undergoing RFA for thyroid nodules.
- Classification into recurrence (N=16) and non-recurrence (N=104) groups based on ultrasound.
- Binary logistic regression and ROC curve analysis to determine risk factors and predictive value.
Main Results:
- The recurrence rate was 13.33%.
- Solitary nodules (WNS), nodule diameter (ND), degree of risk of nodular location (DRN), and recurrent laryngeal nerve (RLN) injury were associated with recurrence.
- WNS, ND, and DRN were identified as independent risk factors, with the combined model showing superior predictive value over individual factors. RLN injury lacked predictive value.
Conclusions:
- Solitary nodules, larger nodule diameter, and risky nodule location are significant risk factors for thyroid nodule recurrence post-RFA.
- Awareness and preventive measures targeting these factors are recommended to minimize recurrence.
- Further research may explore the role of RLN injury in recurrence and refine predictive models.
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