The road to a polio-free Uganda; contribution of the Expanded Program on Immunization Laboratory (EPI-LAB) at Uganda Virus Research Institute
- 1Uganda Virus Research Institute, Plot 51-59 Nakiwogo Road, P. O. Box 49, Entebbe, Uganda.
- 2Ministry of Health, Government of Uganda, Plot 6, Lourdel Road, Nakasero P. O. Box 7272, Kampala, Uganda.
- 3World Health Organization Office, Plot 60 Prince Charles Avenue, Kololo, Kampala.
- 4World Health Organization AFRO, East and Southern Africa (ESA), Nairobi, 45335 Nairobi, Kenya.
- 5World Health Organization AFRO, East and Southern Africa (ESA), Harare, 82-86 Enterprise Road, Highlands, P. O. Box BE 773, Belvedere, Harare, Zimbabwe.
- 0Uganda Virus Research Institute, Plot 51-59 Nakiwogo Road, P. O. Box 49, Entebbe, Uganda.
Related Experiment Videos
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Uganda
Area Of Science
- Virology
- Public Health
- Epidemiology
Background
- Poliomyelitis control in Uganda began in 1950, with acute flaccid paralysis (AFP) surveillance used for wild poliovirus identification.
- The Expanded Program on Immunization Laboratory (EPI-LAB) was established in 1993 at the Uganda Virus Research Institute, becoming a key part of the Global Poliovirus Laboratory Network (GPLN).
Purpose Of The Study
- To document the progress and impact of the EPI-LAB on poliovirus eradication efforts in Uganda.
Main Methods
- Poliovirus detection and identification utilized tissue culture and real-time reverse transcriptase polymerase chain reaction (rRT PCR) for intra-typic differentiation.
- Data were analyzed using EpiInfo™ statistical software within the national AFP database.
Main Results
- Quantitative and qualitative detection of wild and Sabin polioviruses aligned with polio campaigns.
- World Health Organization (WHO) target indicators for AFP surveillance were consistently met throughout the study period.
Conclusions
- Virological tracking and adherence to AFP surveillance indicators have been crucial for maintaining Uganda's wild polio-free status.
- Laboratory surveillance is essential for informing the polio eradication certification process.
Related Experiment Videos
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.