Related Experiment Video
Updated: Jul 3, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
High PEEP extubation as guided by esophageal manometry
Kathryn M Pendleton1, Jacob Fiocchi2, Julia Meyer3
1Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Morbidly obese patients with respiratory failure can be challenging to wean from ventilators. Esophageal manometry-guided PEEP titration improved oxygenation and facilitated extubation in a case study.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Anesthesiology
Background:
- Morbidly obese patients present unique respiratory challenges in the ICU.
- Physiologic changes complicate ventilator weaning and extubation.
- Prolonged mechanical ventilation increases morbidity and mortality.
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