Jove
Visualize
Contact Us

Related Concept Videos

JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
  1. Home
  3. Prognostic Value Of Preoperative Serum Ferritin In Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolization.
  1. Home
  3. Prognostic Value Of Preoperative Serum Ferritin In Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolization.

Related Experiment Video

Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
07:32

Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis

Published on: April 12, 2024

1.3K

Prognostic value of preoperative serum ferritin in hepatocellular carcinoma patients undergoing transarterial

Mi Fan1,2, Tingting Niu1,2, Binwei Lin1

  • 1Departmant of Oncology, NHC Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, Sichuan 621000, P.R. China.

Molecular and Clinical Oncology
|February 15, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Preoperative serum ferritin levels do not reliably predict survival in patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE). Other factors like extrahepatic metastases and vascular invasion are more significant prognostic indicators.

Keywords:
biomarkerhepatocellular carcinomaprognosisserum ferritintransarterial chemoembolization

More Related Videos

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
05:31

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Published on: September 20, 2020

5.6K
Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma
04:09

Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma

Published on: October 10, 2018

8.2K

Related Experiment Videos

Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
07:32

Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis

Published on: April 12, 2024

1.3K
Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
05:31

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Published on: September 20, 2020

5.6K
Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma
04:09

Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma

Published on: October 10, 2018

8.2K

Area of Science:

  • Hepatology
  • Oncology
  • Biochemistry

Background:

  • Hepatocellular carcinoma (HCC) is a major global health concern.
  • Transarterial chemoembolization (TACE) is a standard treatment for unresectable HCC.
  • Identifying reliable prognostic markers for HCC patients undergoing TACE is crucial for treatment planning and patient management.

Purpose of the Study:

  • To investigate the prognostic value of preoperative serum ferritin (SF) levels in patients with HCC undergoing TACE.
  • To compare the predictive power of SF with other established prognostic factors.

Main Methods:

  • Retrospective review of clinicopathological data and biomarkers from 223 HCC patients who underwent TACE.
  • Kaplan-Meier analysis for overall survival (OS) and log-rank tests for significance.
  • Univariate and multivariate Cox proportional hazards regression analyses were employed.

    • Main Results:

    • Extrahepatic metastases (HR=0.490) and vascular invasion (HR=0.373) were identified as independent predictors of OS.
    • Preoperative serum ferritin levels did not independently predict OS (HR=0.810; P=0.309).

    Conclusions:

    • Preoperative serum ferritin is not a reliable biochemical predictor of survival in HCC patients treated with TACE.
    • Prognostic assessment should focus on factors such as extrahepatic spread and vascular invasion.