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Related Experiment Video

Updated: Jul 3, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Monkeypox virus: insights into pathogenesis and laboratory testing methods.

Anoop Kumar¹, Neeraj Singh¹, Anupkumar R Anvikar¹

¹National Institute of Biologicals, A-32, Sector-62, Institutional Area, Noida, U.P. 201309 India.

|February 15, 2024

Summary

This summary is machine-generated.

Monkeypox virus (MPXV) diagnosis is crucial for public health. This review details diagnostic methods like PCR and serology, alongside immunopathogenesis, aiding MPXV control strategies.

Keywords:

LAMP MPXV Monkeypox Pathogenesis Real-time PCR Zoonotic disease

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Last Updated: Jul 3, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting

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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

Published on: April 13, 2009

Area of Science:

Virology
Immunology
Public Health

Background:

Monkeypox virus (MPXV) is a zoonotic pathogen with clinical similarities to smallpox.
MPXV infection triggers a strong innate immune response, aiding viral evasion.
The 2022 WHO global health emergency declaration highlighted the need to differentiate MPXV symptoms.

Purpose of the Study:

To review current diagnostic methods for MPXV.
To highlight advancements in viral isolation, imaging, and sequencing for MPXV detection.
To summarize MPXV immunopathogenesis and its implications for control.

Main Methods:

Comprehensive literature search of PubMed, Medline, and Google Scholar.
Review of diagnostic techniques including polymerase chain reaction (PCR) and serological assays.
Analysis of emerging technologies like next-generation sequencing and imaging for MPXV diagnosis.

Main Results:

Diagnostic methods like PCR and serology are key for MPXV identification.
Innovative technologies enhance diagnostic accuracy and speed.
Understanding MPXV immunopathogenesis is vital for effective management.

Conclusions:

Accurate and timely MPXV diagnosis is essential for public health response.
Advanced diagnostic tools and knowledge of immunopathogenesis are crucial for MPXV control.
This review serves as a resource for clinicians and researchers in developing healthcare strategies.