Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A more appropriate statistical method for analyzing mortality data in shock research.

R G Knapp, W C Wise

    Circulatory Shock
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cystic adamantinoma (ameloblastoma); report of case.

    Journal of oral surgery·2010
    Same author

    Fracture of the mandible; report of case.

    Journal of oral surgery·2010
    Same author

    Cholesteatoma of the maxilla; report of case.

    Journal of oral surgery·2010
    Same author

    Compound composite odontoma of the mandible.

    Journal of oral surgery·2010
    Same author

    ECT remission rates in psychotic versus nonpsychotic depressed patients: a report from CORE.

    The journal of ECT·2001
    Same author

    Is occupational organic solvent exposure a risk factor for scleroderma?

    Arthritis and rheumatism·1998
    Same journal

    Study of septic shock in the non-human primate: relationship of pathophysiological response to therapy with anti-TNF antibody.

    Circulatory shock·1994
    Same journal

    Pentoxifylline inhibits mediator synthesis in an equine in vitro whole blood model of endotoxemia.

    Circulatory shock·1994
    Same journal

    Endocrine and carbohydrate responses to interleukin-6 in vivo.

    Circulatory shock·1994
    Same journal

    Endothelin-1 causes accumulation of leukocytes in the pulmonary circulation.

    Circulatory shock·1994
    Same journal

    Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity.

    Circulatory shock·1994
    Same journal

    Beneficial effects of the phosphodiesterase inhibitors BRL 61063, pentoxifylline, and rolipram in a murine model of endotoxin shock.

    Circulatory shock·1994
    See all related articles

    This study introduces a simple statistical method for comparing survival times in biological research. It addresses limitations of the t-test when data is not normally distributed or includes censored observations.

    Area of Science:

    • Biological research
    • Survival analysis
    • Biostatistics

    Background:

    • Biological research frequently involves analyzing survival times, such as time until death or disease remission.
    • Traditional t-tests are often unsuitable for survival data due to non-Gaussian distributions and censored observations.

    Purpose of the Study:

    • To present a straightforward statistical procedure for comparing survival times between two groups.
    • To offer an alternative to the t-test that accommodates non-normal and censored survival data.

    Main Methods:

    • Description of a statistical procedure specifically designed for survival time analysis.
    • The method accounts for the presence of censored data points, where the event of interest has not yet occurred by the study's end.

    Related Experiment Videos

    Main Results:

    • The described procedure provides a viable alternative for analyzing survival data when t-tests are inappropriate.
    • It effectively handles datasets with non-normally distributed survival times and censored observations.

    Conclusions:

    • A simple statistical method is available for comparing survival times in biological studies.
    • This approach enhances the accuracy of survival data analysis, particularly with censored observations.