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Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
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Long term outcomes of hyperbaric oxygen therapy in post covid condition: longitudinal follow-up of a randomized
Amir Hadanny1,2, Shani Zilberman-Itskovich3,4, Merav Catalogna3
1Sagol Center for Hyperbaric Medicine and Research, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel. amir.had@gmail.com.
Scientific Reports
|February 15, 2024
Summary
Hyperbaric oxygen therapy (HBOT) significantly improves long COVID symptoms, including cognitive, sleep, and pain issues. These benefits persist for at least one year after treatment, enhancing patients' quality of life.
Area of Science:
- Neurology
- Pulmonology
- Rehabilitation Medicine
Background:
- Long COVID syndrome presents persistent cognitive, psychiatric, fatigue, sleep, and pain symptoms.
- Previous studies indicated short-term benefits of hyperbaric oxygen therapy (HBOT) for these symptoms.
Purpose of the Study:
- To evaluate the long-term (1-year) effects of HBOT on patients with long COVID syndrome.
- To assess the durability of HBOT-induced improvements in quality of life, sleep, neuropsychiatric, and pain symptoms.
Main Methods:
- A longitudinal follow-up study of 31 patients with post-COVID-19 cognitive symptoms.
- Patients received 40 daily sessions of HBOT.
- Assessment occurred over one year after the last HBOT session using SF-36 and BSI-18 questionnaires.
Main Results:
- Long-term improvements in quality of life were comparable to short-term outcomes across most SF-36 domains.
- Persistent moderate effect sizes for sleep quality improvements (ES1=0.47-0.79).
- Sustained large effect sizes for neuropsychiatric symptom improvements (BSI-18) and significant long-term reductions in pain severity (ES1=0.69) and interference (ES1=0.83).
Conclusions:
- Hyperbaric oxygen therapy demonstrates persistent positive effects on long COVID symptoms.
- HBOT improves quality of life, sleep quality, and reduces neuropsychiatric and pain symptoms in long COVID patients.
- Clinical benefits of HBOT are maintained for at least one year post-treatment.
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