Spontaneous Coronary Artery Dissection Resulting in Acute Myocardial Infarction With Cardiac Rupture

Takamasa Tanaka1, Ling Li2,3, Stephanie A Dean2

  • 1CVPath Institute, Gaithersburg, Maryland, USA.

JACC. Case Reports
|February 16, 2024
PubMed

Insights

Spontaneous coronary artery dissection (SCAD) rarely causes cardiac rupture, especially in men. This case highlights SCAD as a cause of sudden cardiac death in a male patient without fibromuscular dysplasia.

Area of Science:

  • Cardiology
  • Pathology

Background:

  • Spontaneous coronary artery dissection (SCAD) is a leading cause of myocardial infarction in women.
  • SCAD is frequently associated with fibromuscular dysplasia (FMD).

Observation:

  • A 54-year-old man presented with sudden cardiac death.
  • Autopsy revealed cardiac rupture secondary to SCAD.
  • The patient had no history or evidence of fibromuscular dysplasia.

Findings:

  • This is a rare case of SCAD-induced cardiac rupture in a male patient.
  • Cardiac rupture due to SCAD is an uncommon but fatal complication.
  • Previous reports of SCAD-related cardiac rupture predominantly involved women.

Implications:

  • SCAD should be considered in the differential diagnosis of sudden cardiac death, even in men without FMD.
  • Further research is needed to understand the risk factors and prevalence of SCAD in men.
  • This case underscores the potential for severe cardiovascular events from SCAD beyond typical MI presentations.