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Updated: Jul 3, 2025

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A Rare Association of Epstein-Barr Virus and Budd-Chiari Syndrome
Eli A Zaher1, Mohamed A Ebrahim1, Parth Patel1
1Internal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.
Abstract:
Budd-Chiari syndrome (BCS) is a rare hepatic venous outflow obstruction typically associated with hypercoagulable states. We present a unique case of a 29-year-old male with BCS triggered by a recent Epstein-Barr virus (EBV) infection. Workup unveiled antiphospholipid antibody syndrome as an underlying prothrombotic condition. Diagnostic challenges included inconclusive ultrasound findings, necessitating magnetic resonance imaging for confirmation. This case underscores the importance of considering infectious triggers for venous thromboembolism in BCS. Understanding the potential link between EBV and thrombosis warrants further investigation.
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