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APCs in sinus floor augmentation.

Pascal Valentini1, Elena Calciolari2,3, Sebastien Monlezun1

  • 1Department of Implant Surgery Tattone Hospital, University of Corsica Pasquale Paoli, Institute of Health, Corte, France.

Periodontology 2000
|February 16, 2024
PubMed
Summary
This summary is machine-generated.

Autologous platelet concentrates (APCs) show promise in maxillary sinus lifts, particularly L-PRF alone for lateral approaches. However, more research is needed to confirm efficacy for other methods.

Keywords:
Schneiderian membraneautogenous platelet concentrateslateral window techniquemembrane perforationsinus floor augmentationsinus graftingsinus lifttranscrestal technique

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Area of Science:

  • Dentistry
  • Oral Surgery
  • Regenerative Medicine

Background:

  • Maxillary tooth loss often leads to vertical bone loss, necessitating sinus floor elevation.
  • Autologous platelet concentrates (APCs) are explored for their potential benefits in this procedure.

Purpose of the Study:

  • To review the efficacy of APCs, including Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF), and Plasma-Rich Growth Factor (PRGF), in maxillary sinus elevation procedures.
  • To evaluate APCs as sole grafts versus in combination with bone substitutes.

Main Methods:

  • Narrative review of existing clinical trials and studies on APCs in sinus floor elevation.
  • Analysis of outcomes based on different surgical approaches (transcrestal, one-stage lateral, two-stage lateral) and graft materials.

Main Results:

  • L-PRF shows good feasibility for vertical bone gain in transcrestal and one-stage lateral approaches, with high implant survival and low complications.
  • PRP and PRGF lack sufficient data for definitive conclusions, especially as sole grafts in lateral approaches.
  • APCs alone are not recommended for two-stage lateral approaches due to insufficient stability.
  • APCs combined with bone substitutes may accelerate bone formation but offer no long-term gain.
  • L-PRF membranes show potential for treating sinus membrane perforations.

Conclusions:

  • L-PRF appears to be a predictable grafting material for lateral maxillary sinus grafting when used alone.
  • Further randomized controlled trials (RCTs) are required to compare APCs with various grafting techniques for sinus elevation.