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Recent Advances and Developments in Injectable Conductive Polymer Gels for Bioelectronics.
Sergio J Peñas-Núñez1, David Mecerreyes1,2, Miryam Criado-Gonzalez1
1POLYMAT, University of the Basque Country UPV/EHU, Avda. Tolosa 72, 20018 Donostia-San Sebastián, Spain.
ACS Applied Bio Materials
|February 16, 2024
Summary
Soft matter bioelectronics utilizes self-healing, injectable electroactive polymer gels to bridge biological and electronic interfaces. These advanced gels offer promising applications in tissue engineering and biosensing for future healthcare innovations.
Area of Science:
- Soft matter bioelectronics
- Interdisciplinary research
Background:
- Emerging research frontier merging biology and electronics for healthcare.
- Development of self-healing, biologically mimetic soft gels for bioelectronic interfaces.
- Gels act as a tissue-like interface between electronic devices and biological systems.
Purpose of the Study:
- Comprehensive review of injectable electroactive polymer gels.
- Focus on gels formed via noncovalent and dynamic covalent bonds.
- Overview of synthesis, characterization, and applications.
Main Methods:
- Discussion of hydrogels from conducting polymers (PEDOT, PANi, PPy) with physical or dynamic covalent crosslinking.
- Exploration of hybrid hydrogels incorporating conductive nanomaterials.
- Inclusion of recent advancements in ionogels and eutectogels.
Main Results:
- Electroactive polymer gels offer tunable, self-healing properties.
- Injectable formulations enable seamless integration with biological tissues.
- Hybrid and integrated gel systems show significant potential.
Conclusions:
- Injectable electroactive polymer gels are crucial for advanced bioelectronics.
- These materials hold promise for tissue engineering and biosensing.
- Future research directions include further development of ionogels and eutectogels.

