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Endocrine disruption in crustaceans: New findings and perspectives

Enrique M Rodríguez1

  • 1Universidad de Buenos Aires. CONICET. Instituto de Biodiversidad y Biología Experimental y Aplicada (IBBEA). Facultad de Ciencias Exactas y Naturales, Departamento de Biodiversidad y Biología Experimental. Ciudad Universitaria, C1428EGA, Buenos Aires, Argentina.

Molecular and Cellular Endocrinology
|February 16, 2024
PubMed

Keywords:
DisruptorsGrowthHormonesInvertebratesPhysiologyReproductive output

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Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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Intracellular Hormone Receptors

Lipid-soluble hormones diffuse across the plasma and nuclear membrane of target cells to bind to their specific intracellular receptors. These receptors act as transcription factors that regulate gene expression and protein synthesis in the target cell
Internal Receptors01:31

Internal Receptors

Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.