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Presynaptic Dopamine Dynamics in Striatal Brain Slices with Fast-scan Cyclic Voltammetry
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Published on: January 12, 2012

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Synaptotagmin-7 Counteracts Short-Term Depression during Phasic Dopamine Release.

Joseph J Lebowitz1, Sarah A Kissiwaa1, Kim A Engeln1

  • 1Vollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098.

Eneuro
|February 16, 2024
PubMed
Summary

Synaptotagmin-7 (SYT7) drives short-term facilitation in dopamine release, explaining frequency-dependent dopamine signaling. This presynaptic Ca2+-sensor is crucial for both axonal and somatodendritic dopamine release.

Keywords:
dopamineshort-term plasticitysynaptotagmin

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