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Vascular characterization reveals immunomodulatory targets for brain metastases
Roberta Lugano1, Anna Dimberg1
1Department of Immunology, Genetics and Pathology, Science for Life Laboratory, The Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
Cancer Cell
|February 17, 2024
Abstract
None:
Brain metastases are clinically challenging due to the unique brain microenvironment. In this issue of Cancer Cell, Bejarano et al. use transcriptional profiling and data integration to shed light on the molecular and cellular composition of the vasculature in brain metastases, identifying CD276 as an immunomodulatory target for therapy.

