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Related Concept Videos

Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature
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Diabetic striatopathy: a case report.

Yi Guan1, Lu Yuan1, Lei Yuan2

  • 1Department of Endocrinology, People's Hospital of Fengjie, Chongqing, China.

Neurocase
|February 17, 2024
PubMed
Summary
This summary is machine-generated.

Diabetic striatopathy, a rare hyperglycemic nonketotic hemichorea, causes involuntary movements. This case study shows intensive insulin therapy rapidly resolved symptoms in an elderly patient.

Keywords:
Diabetic striatopathychoreahemichoreahyperglycemicneuroimaging

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Area of Science:

  • Neurology
  • Endocrinology
  • Radiology

Background:

  • Diabetic striatopathy is a rare neurological disorder associated with hyperglycemia.
  • It presents with involuntary movements like chorea or hemiballismus.
  • Basal ganglia abnormalities are characteristic findings on neuroimaging.

Observation:

  • An 86-year-old woman with poorly controlled type 2 diabetes presented with hemichorea.
  • Symptoms included involuntary left limb movements and facial choreiform expressions.
  • Laboratory results indicated hyperglycemia and elevated hemoglobin A1c.

Findings:

  • Neuroimaging revealed T1-hyperintensity in the right basal ganglia.
  • The patient was diagnosed with diabetic striatopathy.
  • Intensive insulin therapy led to a rapid resolution of hemichorea symptoms.

Implications:

  • This case highlights the importance of recognizing diabetic striatopathy in patients with hyperglycemia and movement disorders.
  • Prompt diagnosis and management with insulin therapy can effectively reverse symptoms.
  • Understanding the neuroimaging findings is crucial for accurate diagnosis.