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UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis

Minghe Fan1, Sihan Huo1, Yuyao Guo1

  • 1Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, State Key Laboratory of Molecular Oncology, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China; Peking University International Cancer Institute, Peking University Health Science Center, Beijing 100191, China.

Cell Reports
|February 17, 2024
PubMed

Keywords:
CP: CancerCP: MetabolismHAPDACUDP-glucose dehydrogenaseUGDHautophagyhyaluronic acidp62pancreatic ductal adenocarcinomasequestosome 1

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