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Related Experiment Video

Updated: Jul 2, 2025

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
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Repetitive negative thinking as a unique transdiagnostic risk factor for suicidal ideation.

M M Caudle1, N N Dugas2, K Patel3

  • 1San Diego State University, University of California San Diego Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, United States.

Psychiatry Research
|February 17, 2024
PubMed
Summary
This summary is machine-generated.

Repetitive negative thinking (RNT) is linked to higher suicide risk, even when accounting for depression and anxiety. Targeting RNT may help assess and reduce suicide risk in individuals with mood and anxiety disorders.

Keywords:
Anxiety disordersInternalizing disordersPerseverative thinking

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Mental Health Research

Background:

  • Repetitive negative thinking (RNT) is a common symptom across mood and anxiety disorders.
  • RNT is characterized by frequent, distressing, and uncontrollable thoughts.
  • Previous research on RNT and suicide risk has often focused on specific disorders and RNT subtypes.

Purpose of the Study:

  • To investigate the association between transdiagnostic RNT and suicidal ideation.
  • To determine if RNT is associated with suicide risk independently of disorder-specific clinical symptoms.
  • To explore the clinical utility of assessing RNT for suicide risk stratification.

Main Methods:

  • Fifty-four participants with mood, anxiety, and/or traumatic stress disorders were recruited.
  • Suicidal risk was assessed using the Columbia-Suicide Severity Rating Scale (C-SSRS).
  • Transdiagnostic RNT, depression, and anxiety were measured via self-report questionnaires.

Main Results:

  • Participants were categorized into high or low suicide risk groups based on C-SSRS scores.
  • RNT was found to be uniquely associated with the suicide risk group.
  • This association remained significant after controlling for depression and anxiety severity.

Conclusions:

  • Transdiagnostic RNT is a significant indicator of suicide risk, beyond general symptom severity of depression and anxiety.
  • Assessing RNT may enhance clinical understanding of an individual's suicide risk.
  • Clinical interventions targeting RNT could be beneficial for individuals at high risk of suicide.