Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ion Exchange01:17

Ion Exchange

592
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
592
Ion-Exchange Chromatography01:09

Ion-Exchange Chromatography

492
Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
492
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

1.0K
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
1.0K
¹H NMR: Long-Range Coupling01:27

¹H NMR: Long-Range Coupling

1.7K
The coupling interactions of nuclei across four or more bonds are usually weak, with J values less than 1 Hz. While these are usually not observed in spectra, the presence of multiple bonds along the coupling pathway can result in observable long-range coupling.
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene...
1.7K
Molecular Models02:00

Molecular Models

38.3K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
38.3K
Disubstituted Cyclohexanes: cis-trans Isomerism02:37

Disubstituted Cyclohexanes: cis-trans Isomerism

12.0K
Depending upon the different spatial orientation of the substituents, the disubstituted cycloalkanes exhibit two types of stereoisomers. The cis isomers have the substituents on the same side of the ring, whereas the trans isomers have the substituents on the opposite sides. These stereoisomers exhibit different physical properties and cannot be interconverted without breaking the carbon-carbon bonds.
In cyclohexane, the substituents can occupy different positions generating distinct isomers....
12.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recovery of Linear and Nonlinear Heart Rate Variability Metrics After Short-Term Moderate versus Vigorous Intensity Exercise: A Cross-Sectional Randomized Cross-Over Study.

European journal of sport science·2025
Same author

The Impact of Different Encouragement Strategies on Performance During Maximal Aerobic Exercise Tests: A Scoping Review.

International journal of sports physiology and performance·2025
Same author

Comparing Post-Exercise Hypotension after Different Sprint Interval Training Protocols in a Matched Sample of Younger and Older Adults.

Journal of clinical medicine·2023
Same author

Optimizing sprint interval exercise for post-exercise hypotension: A randomized crossover trial.

European journal of sport science·2022
Same author

Performance and Recovery of Well-Trained Younger and Older Athletes during Different HIIT Protocols.

Sports (Basel, Switzerland)·2022
Same author

Recovery from Different High-Intensity Interval Training Protocols: Comparing Well-Trained Women and Men.

Sports (Basel, Switzerland)·2021

Related Experiment Video

Updated: Jul 2, 2025

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Published on: September 4, 2015

12.4K

On multi-type Cannings models and multi-type exchangeable coalescents.

Martin Möhle1

  • 1Mathematisches Institut, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 10, 72076 Tübingen, Germany.

Theoretical Population Biology
|February 17, 2024
PubMed
Summary

This study analyzes multi-type population models with migration and mutation. As population sizes grow, ancestral processes converge to a multi-type coalescent, revealing insights into population genetics.

Keywords:
ConsistencyExchangeabilityMigrationMulti-type branching processMulti-type coalescent processMutation

More Related Videos

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.0K
Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
08:53

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092

Published on: October 2, 2017

30.0K

Related Experiment Videos

Last Updated: Jul 2, 2025

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Published on: September 4, 2015

12.4K
Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.0K
Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
08:53

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092

Published on: October 2, 2017

30.0K

Area of Science:

  • Population Genetics
  • Mathematical Biology
  • Stochastic Processes

Background:

  • Cannings population models are foundational for studying genetic drift and population structure.
  • Understanding multi-type models is crucial for analyzing populations with distinct subpopulations or types.

Purpose of the Study:

  • To analyze a multi-type neutral Cannings population model with migration.
  • To investigate a related multi-type Cannings model incorporating mutation and varying subpopulation sizes.
  • To examine the asymptotic behavior of these models as population sizes increase.

Main Methods:

  • Analysis of a multi-type neutral Cannings model with fixed subpopulation sizes and migration.
  • Application of coalescent theory, extending single-type models.
  • Decomposition of transition probabilities into reproduction and migration components.
  • Forward and backward time analysis of a model with mutation and stochastic subpopulation sizes.

Main Results:

  • Convergence of the time-scaled ancestral process to a multi-type coalescent under specific conditions.
  • Demonstration of exchangeability and consistency properties in the multi-type coalescent.
  • Identification of multi-type limiting branching processes for large population sizes in the forward-time analysis.
  • Characterization of the backward structure for the model with mutation.

Conclusions:

  • The study provides a rigorous mathematical framework for understanding multi-type population dynamics.
  • The findings contribute to the theoretical underpinnings of population genetics, particularly for structured populations.
  • Asymptotic results offer insights into the behavior of large, complex populations over evolutionary time.