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Size Matching Deceased Donor Livers: The Tampa General Measurement System
Rachel Hogen1, Thasya Smith2, Bethany Jowers2
1Tampa General Hospital Transplant Institute, Tampa, Florida.
Transplantation Proceedings
|February 17, 2024
Summary
A new liver size-matching protocol accurately predicts donor liver fit, minimizing complications like large-for-size syndrome. This effective system improves outcomes in deceased donor liver transplantation.
Area of Science:
- Transplantation Surgery
- Organ Transplantation
- Surgical Imaging
Background:
- Standardized systems for deceased donor liver size measurement are lacking.
- Accurate liver size matching is crucial for successful transplantation.
- Current methods may not reliably predict graft-to-recipient fit.
Purpose of the Study:
- To evaluate the efficacy of a novel liver size-matching protocol.
- To assess the protocol's impact on transplant outcomes.
- To determine the protocol's reliability in predicting donor liver fit.
Main Methods:
- Retrospective analysis of deceased donor liver transplants (Oct 2021-Nov 2022).
- Utilized a protocol comparing donor right hepatic lobe size to recipient right hepatic fossa via cross-sectional imaging.
- Analyzed outcomes including size syndromes, allograft dysfunction, and survival rates.
Main Results:
- 171 patients included; one case of outdated imaging affected fit.
- Large-for-size syndrome occurred in 0.6% of patients; no small-for-size syndrome.
- Early allograft dysfunction observed in 10%, with 7% patient and graft survival rates.
Conclusions:
- The developed measurement system is rapid and effective.
- It reliably predicts donor liver suitability for recipients.
- The protocol is associated with low rates of early allograft dysfunction.
