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Technical note: Minimizing CIED artifacts on a 0.35 T MRI-Linac using deep learning.

Austen N Curcuru1, Deshan Yang2, Hongyu An3

  • 1Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.

Journal of Applied Clinical Medical Physics
|February 18, 2024
PubMed
Summary
This summary is machine-generated.

This study used CycleGAN to reduce implantable cardioverter defibrillator (ICD) artifacts in MRI-guided radiotherapy (MRgRT) images. The AI model significantly improved image quality and target tracking accuracy for better patient treatment.

Keywords:
ICDMRIartifactdeep learning

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Radiotherapy

Background:

  • Implantable cardioverter defibrillators (ICDs) create artifacts that challenge magnetic resonance imaging (MRI)-guided radiotherapy (MRgRT).
  • Artifacts can compromise image quality and treatment accuracy.

Purpose of the Study:

  • To evaluate an unsupervised generative adversarial network (CycleGAN) for mitigating ICD artifacts in balanced steady-state free precession (bSSFP) cine MRIs.
  • To enhance image quality and tracking performance for MRgRT procedures.

Main Methods:

  • A CycleGAN model was trained on bSSFP MRI data from 14 healthy volunteers with simulated ICDs.
  • The model was tested using a Leave-One-Out cross-validation scheme.
  • Image quality and tracking metrics (DSC, TRE, 95% HD, nRMSE, PSNR, MS-SSIM) were evaluated, alongside qualitative assessment on patient data.

Main Results:

  • CycleGAN reconstruction significantly improved whole-heart contour tracking: Dice similarity coefficient (DSC) increased from 0.910 to 0.935, target registration error (TRE) decreased from 4.488 to 2.877 mm, and 95% Hausdorff distance (95% HD) decreased from 10.236 to 7.700 mm.
  • Image quality metrics also improved: normalized root mean square error (nRMSE) decreased from 0.644 to 0.420, multiscale structural similarity (MS-SSIM) increased from 0.779 to 0.819, and peak signal-to-noise ratio (PSNR) increased from 18.744 to 22.368.
  • Qualitative analysis of additional datasets confirmed a reduction in ICD artifacts.

Conclusions:

  • CycleGAN effectively mitigates implantable cardioverter defibrillator (ICD) artifacts in MRI-guided radiotherapy (MRgRT).
  • The AI-driven approach significantly enhances both image quality and tracking accuracy, crucial for precise radiotherapy delivery.