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Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins

Qian Yu1, Zheng Wang1, Yutong Tu2

  • 1Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, 310015, Zhejiang Province, China; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang Province, China.

Bioorganic Chemistry
|February 18, 2024
PubMed

Keywords:
20S proteasomeProteasome activation, IDPsProtein homeostasisUndruggable

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