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Updated: Jul 15, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Soft-tissue, non-osteogenic distraction of the mandible and lower face in bilateral hemifacial microsomia-technical
Artur Nixon-Martins1, Diogo Conduto1, Ana R Gomes1
1Serviço de Cirurgia Plástica, Centro Hospitalar Universitário de Lisboa Norte, Portugal.
Abstract:
The aim of this study is to present a sequential strategy of soft-tissue, non-osteogenic distraction with a novel device, followed by microvascular bony reconstruction for severe cases of mandibular hypoplasia. The case of a 21-year-old woman with Goldenhar syndrome is presented, whose mandible remained severely hypoplastic despite previous attempts at distraction and was not suitable for further osteogenic distraction. Soft tissue deficiency and pin track scarring prevented free fibular transfers. A personalized distractor, anchored to the cranium and the mandibular symphysis, was designed to expand the soft tissues while allowing for physiological temporomandibular joint (TMJ) movement without compression forces. Internal distractors were placed along the osteotomies to prevent condylar luxation. After completion of the soft tissue distraction, the native mandible was resected except for the condyles and reconstructed with two free fibula flaps. This report represents the proof of concept of a sequential approach to severe lower face soft-tissue and bone deficiency, which preserves TMJ function and avoids the transfer of poorly matched skin to the face.
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