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[Bioactive materials in periodontal regeneration].

Ziqin Chen1, Lan Luo1, Kai Luo1

  • 1Fujian Key Laboratory of Oral Diseases, Stomatological Key Laboratory of Fujian College and University, Institute of Stomatology & Laboratory of Oral Tissue Engineering, School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350002, Fujian, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|February 19, 2024
PubMed
Summary

Bioactive materials stimulate cell activity and guide tissue regeneration by creating specific reactions. This review explores their definition, characteristics, and use in periodontal tissue regeneration.

Keywords:
bioactive materialsperiodontal regenerationtissue engineering

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Periodontology

Background:

  • Bioactive materials are advanced biomaterials designed to elicit specific biological or chemical responses at material-tissue interfaces.
  • These interactions are crucial for modulating cellular behavior and promoting tissue repair.
  • Periodontal tissue regeneration is a key area where bioactive materials show significant promise.

Approach:

  • This review consolidates the fundamental definition and properties of bioactive materials.
  • It systematically summarizes their diverse applications within the field of periodontal tissue regeneration.
  • The review synthesizes current knowledge to highlight advancements and future directions.

Key Points:

  • Bioactive materials actively influence the biological environment, unlike inert materials.
  • Their surface chemistry dictates interactions with cells, affecting adhesion, proliferation, and differentiation.
  • Successful application in periodontology relies on understanding material-host interactions for guided regeneration.

Conclusions:

  • Bioactive materials offer a promising strategy for enhancing periodontal tissue regeneration outcomes.
  • Further research into material design and clinical application can optimize their therapeutic potential.
  • This review provides a comprehensive overview for researchers and clinicians in the field.