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Updated: Jul 2, 2025

Dissection of Single Skeletal Muscle Fibers for Immunofluorescent and Morphometric Analyses of Whole-Mount Neuromuscular Junctions
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Decoding muscle-resident Schwann cell dynamics during neuromuscular junction remodeling

Steve D Guzman1,2, Ahmad Abu-Mahfouz1, Carol S Davis1

  • 1Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.

Biorxiv : the Preprint Server for Biology
|February 19, 2024
PubMed
Summary

Muscle-resident Schwann cells are key to neuromuscular junction (NMJ) repair. A novel SPP1-driven interaction between Schwann cell subtypes promotes NMJ reinnervation after nerve injury, crucial for maintaining function.

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