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Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
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Cardiac Optical Coherence Tomography: History, Current Status, and Perspective
Taishi Yonetsu1, Ik-Kyung Jang2
1Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
JACC. Asia
|February 19, 2024
Summary
Intravascular optical coherence tomography (OCT) has advanced cardiovascular medicine by revealing atherosclerosis details and guiding interventions. Future innovations and outcome studies aim to expand its clinical impact.
Area of Science:
- Cardiovascular Medicine
- Medical Imaging
- Vascular Biology
Background:
- Intravascular optical coherence tomography (OCT) has been utilized for over 20 years in cardiovascular medicine.
- OCT provides high-resolution imaging crucial for understanding vascular biology and guiding interventions.
- Its application has significantly improved insights into atherosclerosis and acute coronary syndromes.
Purpose of the Study:
- To review the contributions of intravascular OCT to cardiovascular medicine.
- To highlight OCT's role in vascular biology research and percutaneous coronary intervention (PCI).
- To discuss current challenges and future directions for OCT in clinical practice.
Main Methods:
- Review of literature on intravascular OCT applications in cardiovascular medicine.
- Analysis of OCT's role in studying atherosclerosis pathobiology, including plaque phenotypes.
- Examination of OCT's utility as an adjunctive tool in percutaneous coronary intervention.
Main Results:
- OCT has enhanced understanding of atherosclerosis, plaque erosion, neoatherosclerosis, stent thrombosis, and MINOCA.
- OCT serves as a valuable imaging tool for guiding PCI procedures and optimizing outcomes.
- Challenges include subjective image interpretation and limited clinical outcome data.
Conclusions:
- Intravascular OCT has made substantial contributions to cardiovascular medicine over the past two decades.
- Further advancements, including AI-assisted interpretation and large outcome studies, are expected to broaden OCT's clinical impact.
- Addressing current limitations is key to maximizing the potential of OCT in cardiology.
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