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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Related Experiment Video

Updated: Jul 2, 2025

Zebrafish Keratocyte Explants to Study Collective Cell Migration and Reepithelialization in Cutaneous Wound Healing
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Zebrafish Keratocyte Explants to Study Collective Cell Migration and Reepithelialization in Cutaneous Wound Healing

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Acellular Fish Skin for Deep Dermal Traumatic Wounds Management; Introducing a Novel Dressing.

Esmaeil Biazar1, Reza Zandi2, Saeed Haidari-Keshel3

  • 1Tissue Engineering Group, Department of Biomedical Engineering, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.

Archives of Academic Emergency Medicine
|February 19, 2024
PubMed
Summary
This summary is machine-generated.

Acellular fish skin significantly accelerated deep wound healing and improved scar quality. Combined with platelet-rich fibrin (PRF) and plasma rich in growth factors (PRGF) gels, it offered better functional and aesthetic outcomes than traditional skin grafts.

Area of Science:

  • Regenerative Medicine
  • Wound Healing Research
  • Biomaterials Science

Background:

Keywords:
TransplantationWound healingheterologousplatelet-rich fibrin

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  • Optimal deep wound therapy requires early debridement and coverage to prevent inflammation and promote scar-free healing.
  • Challenges in wound care arise from resource limitations and patient-specific factors, leading to suboptimal outcomes.
  • Current treatments may not fully address the complex needs of deep dermal injuries.