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[Evaluation of renal function in congenital cardiopathies in young children]
Insights
Infants with congenital heart disease show early signs of kidney dysfunction, particularly those with cyanotic forms. Nutritional support is crucial for improving renal function in these vulnerable children.
Area of Science:
- Pediatric Nephrology
- Pediatric Cardiology
Context:
- Congenital heart disease (CHD) affects renal function in infants.
- Early-onset renal affections are observed in infants with CHD.
Purpose:
- To evaluate renal functional parameters in infants with cyanotic and acyanotic congenital heart disease.
- To understand the causes of renal functional deficiency in infants with CHD.
Summary:
- Renal functional deficiency was assessed in 23 infants (1-58 weeks old) with CHD (8 cyanotic, 15 acyanotic).
- Findings indicate renal affections similar to older children with heart disease, with greater deficiency in cyanotic forms.
- This deficiency is linked to maturational retardation and poor trophism, particularly affecting the kidneys.
Impact:
- Highlights the early impact of CHD on renal function in infants.
- Suggests a link between weight deficiency, cyanotic CHD, and renal impairment.
- Recommends appropriate caloric-protein dietary interventions for affected infants.
Abstract:
The authors evaluated some renal functional parameters of 23 children, the ages ranged 1 to 58 weeks; 8 were affected with cyanotic congenital heart disease and 15 with acyanotic forms. They showed the presence, already in this age, of some affections that are quiet similar to those affecting older children with heart disease. They tried to explain the renal functional deficiency in consideration of the literature data also. The authors formed a functional deficiency greater in the cyanotic forms, proportional to the weight deficiency and the same as that described in dystrophic children. They think that this is due to a first year maturational retardation, because of a low trophism of the body, in particular of the kidney. The authors suggest that these patients have to be fed with appropriate caloric-protein diet.