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[Male pseudohermaphroditism].

L Gargantini, G Trifirò, C Bianchi

    La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
    |July 1, 1985
    PubMed
    Summary
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    Male pseudohermaphroditism (MPSH) involves understanding male sexual differentiation and various causes. Early identification, hormonal therapy, surgery, and potential gender reassignment are key management strategies.

    Area of Science:

    • Endocrinology
    • Genetics
    • Developmental Biology

    Context:

    • Male pseudohermaphroditism (MPSH) presents complex diagnostic and therapeutic challenges.
    • Understanding the etiopathogenetic factors is crucial for patient management.

    Purpose:

    • To review the main features of different etiopathogenetic forms of MPSH.
    • To illustrate procedures for early and accurate identification.
    • To discuss treatment options including hormonal therapy, surgery, and gender reassignment.

    Summary:

    • This review covers male sexual differentiation and the diverse etiologies of MPSH.
    • It details diagnostic approaches for timely identification and prognosis.
    • Management strategies, including hormonal treatments, surgical interventions, and gender reassignment for severe cases, are discussed.

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    Impact:

    • Facilitates earlier diagnosis and more accurate prognostication in MPSH cases.
    • Provides a comprehensive overview of current management strategies for clinicians.
    • Informs decisions regarding treatment and potential gender assignment for individuals with MPSH.