Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

Automated Microbial Diagnostics

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A wearable biosensing platform for continuous monitoring of inflammatory and metabolic biomarkers for real-time health tracking and personalized care.

Bioengineering & translational medicine·2026

Same author

A water-based binder for improved adhesion and reversibility of the graphite cathode for sodium dual-ion batteries.

Nanoscale·2026

Same author

TRACE-QUAD: A Multiplexed Electrochemical Platform for Ultrasensitive Detection of Diquat, Paraquat, Glyphosate, and Chlorpyrifos in Drinking Water.

Journal of agricultural and food chemistry·2026

Same author

Dual-cytokine profiling of inflammatory states using a rapid electroanalytical device as a point-of-care sensor platform.

Mikrochimica acta·2026

Same author

A Non-Faradaic Impedimetric Label-Free Immunosensor Integrated with PCCODE Logic for Stratified Monitoring of Post-COVID Conditions.

ACS measurement science au·2025

Same author

Development and benchtop testing of an aptamer-based sweat sensor for CRP detection.

Mikrochimica acta·2025

Search research articles

Related Experiment Video

Updated: May 7, 2026

Combination of Adhesive-tape-based Sampling and Fluorescence in situ Hybridization for Rapid Detection of Salmonella on Fresh Produce

Combination of Adhesive-tape-based Sampling and Fluorescence in situ Hybridization for Rapid Detection of Salmonella on Fresh Produce

Published on: October 18, 2010

PathoSense: a rapid electroanalytical device platform for screening Salmonella in water samples.

Kundan Kumar Mishra¹, Vikram Narayanan Dhamu², Durgasha C Poudyal¹

¹Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA.

Mikrochimica Acta

|February 19, 2024

Summary

A new portable electrochemical sensor rapidly detects Salmonella in water within 9 minutes. This advancement offers enhanced sensitivity and reproducibility for improved food safety and public health monitoring.

Keywords:

Electrochemical impedance spectroscopy (EIS)Electrochemical sensors Label-free detection Potable water analysis Salmonella typhimurium

More Related Videos

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation

Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation

Published on: May 20, 2020

Related Experiment Videos

Last Updated: May 7, 2026

Combination of Adhesive-tape-based Sampling and Fluorescence in situ Hybridization for Rapid Detection of Salmonella on Fresh Produce

Combination of Adhesive-tape-based Sampling and Fluorescence in situ Hybridization for Rapid Detection of Salmonella on Fresh Produce

Published on: October 18, 2010

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation

Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation

Published on: May 20, 2020

Area of Science:

Electrochemistry
Biosensing
Food Safety

Background:

Salmonella contamination poses a significant global health risk, primarily detected through slow culture-based methods.
Current Salmonella detection limitations include insufficient sensitivity and lengthy assay times, hindering rapid response to outbreaks.
There is a critical need for faster, more sensitive methods to detect Salmonella in potable water.

Purpose of the Study:

To develop and evaluate a portable, non-faradaic electrochemical sensing platform for rapid Salmonella detection.
To compare the performance of a pure gold (Au) sensor with a gold-zinc oxide (Au/ZnO) sensor configuration.
To assess the sensitivity, precision, and reproducibility of the developed sensing platform.

Main Methods:

Fabrication of two electrochemical sensor configurations: pure gold (Au) and gold coated with zinc oxide thin film (Au/ZnO).
Detection of Salmonella in potable water samples using the developed sensors.
Evaluation of sensor performance, including limit of detection (LoD), sensitivity, precision, and reproducibility.

Main Results:

The Au/ZnO sensor achieved a lower limit of detection (LoD) of 0.6 CFU/mL compared to the Au sensor's 0.9 CFU/mL.
Both sensor configurations demonstrated high precision and reproducibility, with inter- and intra-study coefficients of variation below 10%.
The sensing platform provided Salmonella detection results within an assay turnaround time of approximately 9 minutes.

Conclusions:

The developed portable electrochemical sensing platform offers a rapid, sensitive, and reproducible method for detecting Salmonella in potable water.
The Au/ZnO sensor configuration shows enhanced performance, indicating the potential of semiconductor integration in electrochemical biosensors.
This technology holds promise for on-site water quality monitoring and mitigating Salmonella outbreaks, advancing food safety and public health.