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Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
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Macroscopy of specimens from the genitourinary system.
1Cellular Pathology, University Hospital of Wales, Cardiff, UK MuraliCardiff@gmail.com.
Journal of Clinical Pathology
|February 19, 2024
Summary
Accurate macroscopic examination of urological specimens is crucial for patient management. This review highlights critical findings and specimen handling for improved histopathology reporting.
Area of Science:
- Uropathology
- Surgical Pathology
- Histopathology
Background:
- Macroscopic specimen examination is vital for accurate histopathology but often lacks sufficient attention and guidance.
- Inconsistent examination can lead to missed critical findings impacting patient management.
Purpose of the Study:
- To review macroscopic examination of common urological specimens.
- To differentiate clinically critical findings from irrelevant ones.
- To emphasize meticulous examination and judicious sampling for accurate diagnosis.
Main Methods:
- Review of literature and common urological specimens.
- Analysis of macroscopic findings and their clinical relevance.
- Discussion of specimen handling and sampling protocols.
Main Results:
- Macroscopic findings are less critical in radical prostatectomy specimens but crucial in orchidectomy specimens (e.g., non-seminomatous components).
- Tumor dimension is prognostic; overall specimen dimensions have limited utility.
- Careful examination is key, as only a small fraction is microscopically analyzed.
- Specific handling is required for testicular cancer lymph node dissections.
- Current prostate sampling protocols need reconsideration.
Conclusions:
- Meticulous macroscopic examination and judicious sampling are essential for accurate urological histopathology.
- Protocols for prostate and testicular cancer specimens require updates to reflect current clinical needs and diagnostic capabilities.
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