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Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

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Published on: March 23, 2014

Eyebrow trichoscopy in leprosy.

Cesar J Ramos-Cavazos¹, Alejandra Villarreal-Martinez¹, Jorge Ocampo-Candiani¹

¹Hospital Universitario Dr. José Eleuterio González, Monterrey, Mexico.

International Journal of Dermatology

|February 20, 2024

Summary

Trichoscopy, a noninvasive scalp and hair analysis, reveals distinct eyebrow changes in leprosy patients. Distal eyebrow findings, including vellus hair and structureless areas, are most affected and easier to identify.

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Area of Science:

Dermatology
Dermatopathology
Trichology

Background:

Trichoscopy offers noninvasive analysis of hair and scalp structures for early alopecia diagnosis.
Leprosy can affect various body structures, including hair and eyebrows.

Purpose of the Study:

To describe trichoscopy findings in the eyebrows of leprosy patients.
To differentiate between medial and distal eyebrow changes in leprosy.
To identify novel trichoscopic markers associated with leprosy.

Main Methods:

A descriptive cross-sectional study was conducted with 25 leprosy patients.
Ten dermoscopic characteristics were evaluated in the medial and distal portions of the eyebrows.
Inter-rater reliability was assessed using Cohen's kappa coefficient.

Main Results:

Vellus hair (96%) and white-yellowish structureless areas (84-92%) were prevalent in both medial and distal eyebrows.
Distal eyebrows also showed pinpoint white dots (92%).
New findings included perifollicular hyperpigmentation and yellow dots.

Conclusions:

This study is the first to detail trichoscopy findings in leprosy, specifically in eyebrow regions.
Medial and distal eyebrow areas are significantly affected, with distal changes being more easily identifiable.
Perifollicular hyperpigmentation and yellow dots are newly identified trichoscopic findings in leprosy patients.