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Factors Associated With Long Survival in Patients With Cancer Admitted to Palliative Care: An Exploratory Study
José António Ferraz-Gonçalves1,2, Adelaide Alves3, Álvaro José Silva1,4
1Faculty of Medicine, Porto University, Porto, Portugal.
Identifying factors for prolonged survival in cancer patients admitted to palliative care is crucial. Higher hemoglobin and creatinine levels were linked to longer survival, while pain and poor performance status indicated shorter prognoses.
Area of Science:
- Palliative Care
- Oncology
- Biostatistics
Background:
- Some cancer patients experience prolonged survival (≥1 year) after palliative care admission.
- Identifying prognostic factors is essential for personalized care planning.
Purpose of the Study:
- To determine factors associated with prolonged survival in cancer patients receiving palliative care.
- To compare characteristics of long-term survivors versus short-term survivors.
Main Methods:
- Retrospective case-control study using electronic health records (2012-2018).
- Compared patients surviving ≥1 year (cases) with those surviving ≤6 months (controls).
- Multivariable analysis to identify significant prognostic factors.
Main Results:
- 111 cases (6.4%) and 363 controls (21.1%) were analyzed.
- Higher hemoglobin (≥10.6 g/dL) and creatinine (>95 µmol/L) correlated with longer survival.
- Abnormal cognition, pain, anorexia, liver metastases, ECOG status >1, and high neutrophil/lymphocyte ratio (≥3.43) were associated with shorter survival.
Conclusions:
- Several clinical and laboratory factors significantly predict prolonged survival in palliative care cancer patients.
- Findings require validation in larger, prospective studies for clinical application.
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