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Visual Perception in Children with a History of Hypoglycemia due to Hyperinsulinism

Mohammad Reza Ghazavi1, Jafar Nasiri1, Azin Momeni2

  • 1Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan, Iran.

Iranian Journal of Child Neurology
|February 20, 2024
PubMed

Insights

Children with hyperinsulinism show significantly impaired visual perception compared to healthy peers. Early screening for visual perceptual disorders is recommended for children with hyperinsulinism to guide rehabilitation.

Area of Science:

  • Pediatric Endocrinology
  • Neuroscience
  • Ophthalmology

Background:

  • Hyperinsulinism involves abnormal insulin secretion leading to hypoglycemia, particularly affecting the brain's occipital lobe.
  • Hypoglycemia can cause damage to the occipital lobe, which is crucial for visual perception.
  • Understanding visual perception deficits in children with hyperinsulinism is essential for early intervention.

Purpose of the Study:

  • To investigate visual perception abilities in children diagnosed with hyperinsulinism.
  • To compare visual perception skills between children with hyperinsulinism and a healthy control group.

Main Methods:

  • A cross-sectional control study conducted in Isfahan, Iran, in 2020.
  • Participants included 20 children (aged 4-13 years) with hyperinsulinism and 20 age- and gender-matched healthy controls.
  • The Test of Visual Perceptual Skills (non-motor) Third Edition was used for assessment in both groups.

Main Results:

  • Children with hyperinsulinism had a significantly lower mean visual perceptual quotient (80.50±26.74) compared to controls (116.50±7.56) (p<0.001).
  • All areas of visual perception were found to be weaker in children with hyperinsulinism than in healthy children.

Conclusions:

  • Children suffering from hyperinsulinism exhibit significant deficits in visual perception.
  • Routine screening for visual perceptual disorders is recommended for children with hyperinsulinism.
  • Early identification can facilitate the implementation of targeted rehabilitation programs.
Abstract

Keywords:
HyperinsulinismHypoglycemiaOccipital LobeVisual Perception

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