A computational model to analyze the impact of birth weight-nutritional status pair on disease development and

Zakir Hussain1, Malaya Dutta Borah1

  • 1Department of Computer Science and Engineering, National Institute of Technology Silchar, NIT Road, Cachar, Silchar, Assam 788010 India.

Insights

Optimal birth weight and nutrition are key for disease resistance and recovery. Low birth weight with malnutrition poses the highest risk for disease development and poor recovery outcomes.

Area of Science:

  • Computational biology
  • Health informatics
  • Disease modeling

Background:

  • Birth weight and nutritional status are critical determinants of an individual's health.
  • Understanding their combined impact on disease is essential for public health strategies.

Purpose of the Study:

  • To analyze the combined effects of birth weight and nutritional status on disease development and recovery.
  • To computationally establish the impact of specific birth weight-nutritional status pairs on health outcomes.

Main Methods:

  • Development of a two-phase computational model.
  • Phase 1: Machine learning models (Gradient Boosting, SVM) used to predict birth weight from a public dataset.
  • Phase 2: Integration of predicted birth weight with nutritional status data to analyze disease dynamics using differential equations.

Main Results:

  • Gradient Boosting with Information Gain and SVM with Chi-square test were optimal for birth weight prediction.
  • Normal birth weight and normal nutritional status showed the best outcomes for disease resistance and recovery.
  • Low birth weight with malnutrition was worst for disease development; high birth weight with malnutrition was worst for recovery.

Conclusions:

  • Computational analysis confirms the significant impact of birth weight-nutritional status pairs on disease development and recovery.
  • Findings highlight the importance of adequate birth weight and nutrition for overall health.
  • Results can inform public health policies and healthcare resource allocation.
Abstract