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Updated: Jul 2, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
A rare synchronous presentation of primary malignant melanoma in cervix and vagina
Usha K N Pai1, Sreekumar Pillai2, N R Arunkumar3
1Department of Pathology, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Kuala Lumpur, MalaysiaSurgical Oncology, Jubilee Mission Medical College and Research Institute, Kerala, India.
Abstract:
Malignant melanoma, primarily a cutaneous malignancy, can also involve mucosal surfaces and constitutes 2% to 7% of all gynecological malignancies. Primary melanoma of the uterine cervix is an uncommon tumor and has poor prognosis. In the female genital tract, the synchronous occurrence of primary malignant melanoma in the cervix and vagina is rare. We report a case of a 48-year-old female patient who presented with a blackish vaginal mass and associated growth in the cervix. Biopsy from the vaginal mass was reported as malignant melanoma. Following this, she underwent radical surgery and adjuvant radiotherapy. After 12 months, the patient is doing well.

