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Determination of quality of life-related health utilities for surgical complications in ovarian cancer
Rudy S Suidan1, Charlotte C Sun1, Amy K Schneider1
1Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, PO Box 301439, Houston, TX 77230-1429, USA.
Gynecologic Oncology
|February 20, 2024
Summary
This study quantifies health utilities for ovarian cancer surgical complications. Patients and clinicians value outcomes differently, impacting quality-adjusted life years and shared decision-making.
Area of Science:
- Oncology
- Health Economics
- Patient-Reported Outcomes
Background:
- Ovarian cancer treatment involves significant surgical interventions.
- Understanding patient and clinician perspectives on surgical complication severity is crucial for treatment evaluation.
Purpose of the Study:
- To assess health state utilities for various surgical complications in ovarian cancer.
- To compare utility values between ovarian cancer patients, clinicians, and non-cancer controls.
Main Methods:
- Utilized visual analog scale (VAS) and time trade-off (TTO) methods to assess utilities for 14 surgical complications.
- Collected data from 50 ovarian cancer patients, 50 clinicians, and 50 controls.
Main Results:
- Clinicians reported more favorable utility scores than patients via VAS (0.49 vs. 0.43).
- Patients who experienced ostomy reported higher utility (0.7) than those who had not (0.2).
- Bleeding requiring transfusion was viewed most favorably; genito-intestinal fistula was least favorable.
Conclusions:
- Established health state utilities for ovarian cancer surgical complications.
- These utilities are valuable for cost-effectiveness analyses and quality-adjusted outcome determination.
- Findings can aid in patient counseling and shared decision-making processes.
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