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Cardiovascular disease as part of Long COVID: a systematic review

Vasiliki Tsampasian1, Maria Bäck2,3, Marco Bernardi4

  • 1Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.

European Journal of Preventive Cardiology
|February 21, 2024
PubMed

Insights

Long COVID syndrome significantly impacts cardiovascular health, leading to various cardiac complications. This review synthesizes current evidence on Long COVID

Area of Science:

  • Cardiology and Infectious Diseases
  • Multisystemic sequelae of viral infections

Background:

  • Long COVID syndrome affects millions globally, with significant cardiovascular implications.
  • Understanding the diverse cardiovascular manifestations is crucial for patient management.

Approach:

  • Conducted a narrative review with an in-depth systematic literature search.
  • Analyzed 78 studies from PubMed and Cochrane databases.
  • Critically evaluated pathophysiology, manifestations, risk factors, and treatments.

Key Points:

  • Identified a wide range of cardiovascular sequelae associated with Long COVID.
  • Assessed potential mechanistic pathways and risk factors contributing to cardiac complications.
  • Examined current diagnostic approaches, preventive strategies, and therapeutic options.

Conclusions:

  • This review consolidates evidence on cardiovascular manifestations of Long COVID.
  • Highlights the need for comprehensive understanding and management of cardiac issues post-COVID-19 infection.
Abstract

Keywords:
Cardiac long COVIDCardiovascular diseaseLong COVIDPost COVID-19 conditionSARS-COV-2

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